SGMS2 Antibody

Polyclonal Antibody

Wet Ice

SGMS2

Liquid

Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.

NP_001129729

Polyclonal

Recombinant Human Phosphatidylcholine:ceramide cholinephosphotransferase 2 protein (1-79AA)

Varies by lot. See vial for concentration.