BNIP3L Antibody

ArtNr	OACA06598
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria."Kitamura N., Nakamura Y., Miyamoto Y., Miyamoto T., Kabu K., Yoshida M., Futamura M., Ichinose S., Arakawa H.PLoS ONE 6:E16060-E16060(2011) . [2]Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.Sci. Signal. 3:RA3-RA3(2010). [3]Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.Cell 127:635-648(2006).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	adenovirus E1B19k-binding protein B5;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like;BCL2/adenovirus E1B 19-kd protein-interacting protein 3a;BCL2/adenovirus E1B 19kDa interacting protein 3 like;BNIP3a;NIP3L;NIP3-like protein X;NIP-3-like protein X;NIX.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	BNIP3L
Gene Fullname	BCL2 interacting protein 3 like
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Nucleotide accession_num	NM_001330491
Protein accession_num	NP_001317420
Protein name	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein (1-187AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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