MCM6 Antibody

ArtNr	OACA06694
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6."Wei Z., Liu C., Wu X., Xu N., Zhou B., Liang C., Zhu G.J. Biol. Chem. 285:12469-12473(2010). [2]N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB." Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012). [3]Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA replication licensing factor MCM6;MCG40308;MCM6 minichromosome maintenance deficient 6 (MIS5 homolog,S. pombe);minichromosome maintenance deficient (mis5,S. pombe) 6;Mis5;P105MCM.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MCM6
Gene Fullname	minichromosome maintenance complex component 6
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Nucleotide accession_num	NM_005915
Protein accession_num	NP_005906
Protein name	DNA replication licensing factor MCM6
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human DNA replication licensing factor MCM6 protein (562-821AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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