HSD11B1 Antibody

ArtNr	OACA06910
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot ELISA Lipid & Fatty Acid Transport Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism."Draper N., Echwald S.M., Lavery G.G., Walker E.A., Fraser R., Davies E., Soerensen T.I.A., Astrup A., Adamski J., Hewison M., Connell J.M., Pedersen O., Stewart P.M.J. Clin. Endocrinol. Metab. 87:4984-4990(2002). [2]"The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization." Tannin G.M., Agarwal A.K., Monder C., New M.I., White P.C.J. Biol. Chem. 266:16653-16658(1991). [3]"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	11-beta-HSD1;11-beta-hydroxysteroid dehydrogenase 1;11-DH;corticosteroid 11-beta-dehydrogenase isozyme 1;CORTRD2;HDL;HSD11;HSD11B;HSD11L;SDR26C1;short chain dehydrogenase/reductase family 26C member 1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	HSD11B1
Gene Fullname	hydroxysteroid 11-beta dehydrogenase 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).
Nucleotide accession_num	NM_001206741
Protein accession_num	NP_001193670
Protein name	Corticosteroid 11-beta-dehydrogenase isozyme 1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Corticosteroid 11-beta-dehydrogenase isozyme 1 protein (25-292AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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