PRMT2 Antibody

ArtNr	OACA07158
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Neural Transcription Factors Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Breast Cancer Immunostaining Bone Cancer Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"Solution structure of the SH3 domain of the protein arginine N-methyltransferase 2." RIKEN structural genomics initiative (RSGI)Submitted (OCT-2005). [2]"Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4."Lakowski T.M., Frankel A.Biochem. J. 421:253-261(2009). [3]"PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor."Meyer R., Wolf S.S., Obendorf M.J. Steroid Biochem. Mol. Biol. 107:1-14(2007).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	histone-arginine N-methyltransferase PRMT2;HMT1 (hnRNP methyltransferase,S. cerevisiae)-like 1;HMT1 hnRNP methyltransferase-like 1;HRMT1L1;PRMT2 alpha;PRMT2 beta;PRMT2 gamma;protein arginine N-methyltransferase 2.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PRMT2
Gene Fullname	protein arginine methyltransferase 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.
Nucleotide accession_num	NM_001242864
Protein accession_num	NP_001229793
Protein name	Protein arginine N-methyltransferase 2
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Protein arginine N-methyltransferase 2 protein (1-300AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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