RNF125 Antibody

ArtNr	OACA07162
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Astrocytoma By Organ Breast Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation." Zhao H., Li C.C., Pardo J., Chu P.C., Liao C.X., Huang J., Dong J.G., Zhou X., Huang Q., Huang B.C.B., Bennett M.K., Molineaux S.M., Lu H., Daniel-Issakani S., Payan D.G., Masuda E.S. J. Immunol. 174:5288-5297(2005). [2]"Systematic identification of regulatory proteins critical for T-cell activation." Chu P., Pardo J., Zhao H., Li C.C., Pali E., Shen M.M., Qu K., Yu S.X., Huang B.C.B., Yu P., Masuda E.S., Molineaux S.M., Kolbinger F., Aversa G., de Vries J., Payan D.G., Liao X.C. J. Biol. 2:21.1-21.16(2003). [3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase RNF125;RING finger protein 125;ring finger protein 125,E3 ubiquitin protein ligase;T-cell RING activation protein 1;T-cell ring protein identified in activation screen;TNORS;TRAC1;TRAC-1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	RNF125
Gene Fullname	ring finger protein 125
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53 (PubMed:15843525, PubMed:17460044, PubMed:17643463, PubMed:26027934, PubMed:26471729, PubMed:25591766, PubMed:27411375). Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation (PubMed:17460044, PubMed:26471729). Mediates ubiquitination and subsequent degradation of p53/TP53 (PubMed:25591766). Mediates ubiquitination and subsequent degradation of JAK1 (PubMed:26027934). Acts as a positive regulator of T-cell activation (PubMed:15843525).
Nucleotide accession_num	NM_017831
Protein accession_num	NP_060301
Protein name	E3 ubiquitin-protein ligase RNF125
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human E3 ubiquitin-protein ligase RNF125 protein (1-232AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

OACA07162-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 50 ul

lieferbar

Lieferung vsl. bis 25.12.2025

Express-Lieferung: 2 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern