FKBP4 Antibody

ArtNr	OACA07193
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Neuroscience Neuroinflammation Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Immunoprecipitation Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex." Wu B., Li P., Liu Y., Lou Z., Ding Y., Shu C., Ye S., Bartlam M., Shen B., Rao Z. Proc. Natl. Acad. Sci. U.S.A. 101:8348-8353(2004). [2]"Structure of the N-terminal domain of human FKBP52."Li P., Ding Y., Wu B., Shu C., Shen B., Rao Z.Acta Crystallogr. D 59:16-22(2003). [3]"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	51 kDa FK506-binding protein;52 kDa FK506-binding protein;59 kDa immunophilin;FK506 binding protein 4,59kDa;FK506-binding protein 4;FKBP51;FKBP52;FKBP59;HBI;HSP binding immunophilin;Hsp56;HSP-binding immunophilin;Immunophilin FKBP52;p52;peptidylprolyl cis-trans isomerase;peptidyl-prolyl cis-trans isomerase FKBP4;PPIase;rotamase;T-cell FK506-binding protein,59kD.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	FKBP4
Gene Fullname	FKBP prolyl isomerase 4
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
Nucleotide accession_num	NM_002014
Protein accession_num	NP_002005
Protein name	Peptidyl-prolyl cis-trans isomerase FKBP4
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP4 protein (220-459AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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