DCAF7 Antibody

ArtNr	OACA07288
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Blastoma Sarcoma Immunohistochemistry Western Blot ELISA Immunofluorescence Cardiovascular Research Hypertension Primary Antibodies By Organ Bladder Cancer Immunostaining Stem Cell Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"ZNF703 gene amplification at 8p12 specifies luminal B breast cancer." Sircoulomb F., Nicolas N., Ferrari A., Finetti P., Bekhouche I., Rousselet E., Lonigro A., Adelaide J., Baudelet E., Esteyries S., Wicinski J., Audebert S., Charafe-Jauffret E., Jacquemier J., Lopez M., Borg J.P., Sotiriou C., Popovici C. Ginestier C. EMBO Mol. Med. 3:153-166(2010). [2]"Initial characterization of the human central proteome."Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2010). [3]"A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1."Jin J., Arias E.E., Chen J., Harper J.W., Walter J.C.Mol. Cell 23:709-721(2005).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AN11;DDB1- and CUL4-associated factor 7;HAN11;human anthocyanin;seven-WD-repeat protein of the AN11 family-1;SWAN-1;WD repeat-containing protein 68;WD repeat-containing protein An11 homolog;WDR68.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DCAF7
Gene Fullname	DDB1 and CUL4 associated factor 7
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Nucleotide accession_num	NM_005828
Protein accession_num	NP_005819
Protein name	DDB1- and CUL4-associated factor 7
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human DDB1- and CUL4-associated factor 7 protein (1-342AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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