ENTPD5 Antibody

ArtNr	OACA07420
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Metabolism Diabetes Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Immunohistochemistry Immunoprecipitation Western Blot ELISA Autophagy Cardiovascular Research Proliferation Myocardial Infarction Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"The human PCPH proto-oncogene: cDNA identification, primary structure, chromosomal mapping, and expression in normal and tumor cells."Recio J.A., Zambrano N., Pena L., Reig J.A., Rhoads A., Rouzaut A., Notario V.Mol. Carcinog. 27:229-236(2000). [2]"Bacterial expression, folding, purification and characterization of soluble NTPDase5 (CD39L4) ecto-nucleotidase."Murphy-Piedmonte D.M., Crawford P.A., Kirley T.L. Biochim. Biophys. Acta 1747:251-259(2005). [3]"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."Liu T., Qian W.-J., Gritsenko M.A., Camp D.G. II, Monroe M.E., Moore R.J., Smith R.D.J. Proteome Res. 4:2070-2080(2005).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD39 antigen-like 4;CD39L4;CD39-like 4;ectonucleoside triphosphate diphosphohydrolase 5;ER-UDPase;GDPase ENTPD5;guanosine-diphosphatase ENTPD5;NTPDase 5;NTPDase-5;nucleoside diphosphatase;PCPH;Pcph proto-oncogene protein;proto-oncogene CPH;UDPase ENTPD5;uridine-diphosphatase ENTPD5.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ENTPD5
Gene Fullname	ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Nucleotide accession_num	NM_001249
Protein accession_num	NP_001240
Protein name	Ectonucleoside triphosphate diphosphohydrolase 5
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 5 protein (149-428AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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