NR2C2 Antibody

ArtNr	OACA07440
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Hematology Leukemia Immunohistochemistry ELISA Cardiovascular Research Atherosclerosis Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"NLRP10 enhances Shigella-induced pro-inflammatory responses." Lautz K., Damm A., Menning M., Wenger J., Adam A.C., Zigrino P., Kremmer E., Kufer T.A.Cell. Microbiol. 14:1568-1583(2012). [2]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.Sci. Signal. 3:RA3-RA3(2010). [3]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.Sci. Signal. 2:RA46-RA46(2009).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Nuclear hormone receptor TR4;nuclear receptor subfamily 2 group C member 2;orphan nuclear receptor TAK1;orphan nuclear receptor TR4;orphan receptor TR4;TAK1;testicular nuclear receptor 4;Testicular receptor 4;TR4.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	NR2C2
Gene Fullname	nuclear receptor subfamily 2 group C member 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
Nucleotide accession_num	NM_001291694
Protein accession_num	NP_001278623
Protein name	Nuclear receptor subfamily 2 group C member 2
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Nuclear receptor subfamily 2 group C member 2 protein (240-380AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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