SEMA4C Antibody

ArtNr	OACA07519
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer Immunostaining small GTPases Rho Subfamily
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). [2]"Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Hattori A., Kondo Y., Okumura K., Ohara O.DNA Res. 7:347-355(2000). [3]"Sema4C participates in myogenic differentiation in vivo and in vitro through the p38 MAPK pathway."Wu H., Wang X., Liu S., Wu Y., Zhao T., Chen X., Zhu L., Wu Y., Ding X., Peng X., Yuan J., Wang X., Fan W., Fan M.Eur. J. Cell Biol. 86:331-344(2007).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	M-Sema F;M-SEMA-F;sema domain,immunoglobulin domain (Ig),transmembrane domain (TM) and short cytoplasmic domain,(semaphorin) 4C;SEMACL1;SEMAF;SEMAI;semaphorin-4C.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	SEMA4C
Gene Fullname	semaphorin 4C
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Nucleotide accession_num	NM_017789
Protein accession_num	NP_060259
Protein name	Semaphorin-4C
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Semaphorin-4C protein (749-833AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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