MEF2C Antibody

ArtNr	OACA07588
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Neural Development Antibodies By Cell Type Blastoma Hematology Leukemia Lymphoma Myeloma Sarcoma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"Identification and characterization of a new splice variant of human MEF2C." Infantino V., Convertini P., Palmieri F., Iacobazzi V. Submitted (MAY-2008). [2]"The full-ORF clone resource of the German cDNA consortium."Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.BMC Genomics 8:399-399(2007).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C5DELq14.3;DEL5q14.3;MADS box transcription enhancer factor 2,polypeptide C;Myocyte enhancer factor 2C;myocyte-specific enhancer factor 2C;NEDHSIL.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MEF2C
Gene Fullname	myocyte enhancer factor 2C
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Nucleotide accession_num	NM_001131005
Protein accession_num	NP_001124477
Protein name	Myocyte-specific enhancer factor 2C
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Myocyte-specific enhancer factor 2C protein (170-380AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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