GOSR1 Antibody

ArtNr	OACA07596
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry ELISA Primary Antibodies Immunostaining Glial Cell Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. Nusbaum C. Nature 440:1045-1049(2006). [2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). [3]"Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network."Tai G., Lu L., Wang T.L., Tang B.L., Goud B., Johannes L., Hong W.Mol. Biol. Cell 15:4011-4022(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	28 kDa cis-Golgi SNARE p28;28 kDa Golgi SNARE protein;cis-golgi SNARE;golgi integral membrane protein 2;Golgi SNAP receptor complex member 1;Golgi SNARE 28 kDa;GOLIM2;GOS28;GOS-28;GOS28/P28;GS28;P28.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GOSR1
Gene Fullname	golgi SNAP receptor complex member 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
Nucleotide accession_num	NM_001007024
Protein accession_num	NP_001007025
Protein name	Golgi SNAP receptor complex member 1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Golgi SNAP receptor complex member 1 protein (1-115AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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