ELF4 Antibody

ArtNr	OACA07841
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Development Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Immunohistochemistry ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"The DNA sequence of the human X chromosome." Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. Bentley D.R.Nature 434:325-337(2005). [2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). [3]"Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells."Hedvat C.V., Yao J., Sokolic R.A., Nimer S.D.J. Biol. Chem. 279:6395-6400(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E74-like factor 4;E74-like factor 4 (ets domain transcription factor);ELFR;ETS-related transcription factor Elf-4;MEF;myeloid Elf-1-like factor.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ELF4
Gene Fullname	E74 like ETS transcription factor 4
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Nucleotide accession_num	NM_001127197
Protein accession_num	NP_001120669
Protein name	ETS-related transcription factor Elf-4
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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