MEOX1 Antibody

ArtNr	OACA08341
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Mesothelioma Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Primary Antibodies By Organ Lung Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	homeobox protein MOX-1;KFS2;Mesenchyme homeobox 1;MOX1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MEOX1
Gene Fullname	mesenchyme homeobox 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
Nucleotide accession_num	NM_001040002
Protein accession_num	NP_001035091
Protein name	Homeobox protein MOX-1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Homeobox protein MOX-1 protein (1-254AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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