MARK1 Antibody

ArtNr	OACA08910
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Blastoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Stem Cell Markers Astrocyte Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MAP/microtubule affinity-regulating kinase 1;MARK;PAR1 homolog c;Par1c;Par-1c;serine/threonine-protein kinase MARK1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MARK1
Gene Fullname	microtubule affinity regulating kinase 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Serine/threonine-protein kinase (PubMed:23666762). Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Nucleotide accession_num	NM_001286128
Protein accession_num	NP_001273057
Protein name	Serine/threonine-protein kinase MARK1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Serine/threonine-protein kinase MARK1 protein (560-700AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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Menge: 50 ul

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Lieferung vsl. bis 25.12.2025

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