DNAJB2 Antibody

ArtNr	OACA09003
Hersteller	AVIVA Systems Biology
Menge	50 ul
Kategorie	Neuroscience Neuroinflammation Metabolism Diabetes Neural Mitochondrial Function Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Obesity Cell Status Cell Metabolism Immunohistochemistry Western Blot ELISA Autophagy Oxidative Stress Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CMT2T;DnaJ (Hsp40) homolog,subfamily B,member 2;dnaJ homolog subfamily B member 2;dnaJ protein homolog 1;DSMA5;heat shock 40 kDa protein 3;heat shock protein J1;heat shock protein,neuronal DNAJ-like 1;HSJ1;HSJ-1;HSPF3.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DNAJB2
Gene Fullname	DnaJ heat shock protein family (Hsp40) member B2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Functions as a co-chaperone, regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family (PubMed:7957263, PubMed:22219199). In parallel, also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins (PubMed:15936278, PubMed:21625540). Thereby, may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT, MC4R, PRKN, RHO and SOD1 and be crucial for many biological processes (PubMed:12754272, PubMed:20889486, PubMed:21719532, PubMed:22396390, PubMed:24023695). Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins (PubMed:15936278).
Nucleotide accession_num	NM_001039550
Protein accession_num	NP_001034639
Protein name	DnaJ homolog subfamily B member 2
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human DnaJ homolog subfamily B member 2 protein (215-324AA)
Formulation	PBS with, 50% glycerol, pH7.3.

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Lieferung vsl. bis 25.12.2025

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