FAM65B Antibody

ArtNr	OACA09375
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Antibodies Cell Biology Cytoskeleton Immunohistochemistry ELISA Primary Antibodies Immunostaining small GTPases Rho Subfamily
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C6orf32;DFNB104;DIFF40;DIFF48;FAM65B;family with sequence similarity 65 member B;myogenesis-related and NCAM-associated protein homolog;MYONAP;PL48;protein FAM65B;rho family-interacting cell polarization regulator 2.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	IHC 1:20~200
Gene symbol	RIPOR2
Gene Fullname	RHO family interacting cell polarization regulator 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (PubMed:17150207, PubMed:24687993, PubMed:23241886, PubMed:24958875, PubMed:25588844, PubMed:27556504). Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration (PubMed:23241886). Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maintaining the structural organization of the basal domain of stereocilia (By similarity). Involved in mechanosensory hair cell function (By similarity). Required for normal hearing (PubMed:24958875).
Nucleotide accession_num	NM_001286447
Protein accession_num	NP_001273376
Protein name	Rho family-interacting cell polarization regulator 2
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Rho family-interacting cell polarization regulator 2 protein (1-250AA)

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OACA09375-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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