BAZ2A Antibody

ArtNr	OACA09710
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Neural Epigenetics Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	bromodomain adjacent to zinc finger domain protein 2A;hWALp3;TIP5;transcription termination factor I-interacting protein 5;TTF-I interacting peptide 5;TTF-I-interacting protein 5;WALp3.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	BAZ2A
Gene Fullname	bromodomain adjacent to zinc finger domain 2A
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity).
Nucleotide accession_num	NM_013449
Protein accession_num	NP_038477
Protein name	Bromodomain adjacent to zinc finger domain protein 2A
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Bromodomain adjacent to zinc finger domain protein 2A protein (97-266AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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OACA09710-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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