HCFC1 Antibody

ArtNr	OACA09781
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C1 factor;CFF;HCF;HCF1;HCF-1;HFC1;host cell factor 1;MRX3;PPP1R89;protein phosphatase 1,regulatory subunit 89;VCAF;VP16 accessory protein;VP16-accessory protein.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	HCFC1
Gene Fullname	host cell factor C1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Involved in control of the cell cycle (PubMed:10629049, PubMed:10779346, PubMed:15190068, PubMed:16624878, PubMed:23629655). Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (PubMed:10675337, PubMed:12244100). Coactivator for EGR2 and GABP2 (PubMed:12244100, PubMed:14532282). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together (PubMed:12670868). Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1 (PubMed:20200153). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Recruits KMT2E/MLL5 to E2F1 responsive promoters promoting transcriptional activation and thereby facilitates G1 to S phase transition (PubMed:23629655).
Nucleotide accession_num	NM_005334
Protein accession_num	NP_005325
Protein name	Host cell factor 1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Host cell factor 1 protein (201-428AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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OACA09781-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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