CCND2 Antibody

ArtNr	OACA10135
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Colorectal Cancer Immunostaining Bone Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	G1/S-specific cyclin-D2;KIAK0002;MPPH3.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CCND2
Gene Fullname	cyclin D2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
Nucleotide accession_num	NM_001759
Protein accession_num	NP_001750
Protein name	G1/S-specific cyclin-D2
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human G1/S-specific cyclin-D2 protein (215-285AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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OACA10135-datasheet.pdf

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Menge: 50 ug

lieferbar

Lieferung vsl. bis 25.12.2025

Express-Lieferung: 2 Tage sparen

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