PTBP1 Antibody

ArtNr	OACA10278
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	57 kDa RNA-binding protein PPTB-1;heterogeneous nuclear ribonucleoprotein I;heterogeneous nuclear ribonucleoprotein polypeptide I;hnRNP I;HNRNPI;HNRNP-I;HNRPI;polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I);polypyrimidine tract-binding protein 1;pPTB;PTB;PTB-1;PTB2;PTB3;PTB4;PTB-T;RNA-binding protein.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PTBP1
Gene Fullname	polypyrimidine tract binding protein 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Nucleotide accession_num	NM_002819
Protein accession_num	NP_002810
Protein name	Polypyrimidine tract-binding protein 1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Polypyrimidine tract-binding protein 1 protein (135-292AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4

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OACA10278-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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