BECN1 Antibody

ArtNr	OACA10550
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Necrosis Apoptosis Adenocarcinoma Cytoskeleton Mesothelioma Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Cardiovascular Research Proliferation Myocardial Infarction Motor proteins Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ATG6;ATG6 autophagy related 6 homolog;beclin 1 (coiled-coil,moesin-like BCL2-interacting protein);beclin 1,autophagy related;beclin1;beclin-1;coiled-coil myosin-like BCL2-interacting protein;Protein GT197;testis secretory sperm-binding protein Li 215e;VPS30.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	BECN1
Gene Fullname	beclin 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Plays a central role in autophagy (PubMed:23184933, PubMed:28445460). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530, PubMed:26783301). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
Nucleotide accession_num	NM_001313998
Protein accession_num	NP_001300927
Protein name	Beclin-1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Beclin-1 protein (1-100AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4

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OACA10550-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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