MYO7A Antibody

ArtNr	OACA10566
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules Antibodies By Cell Type Carcinoma Cell Biology Cell Movement Cell Adhesion Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DFNA11;DFNB2;myosin VIIA (Usher syndrome 1B (autosomal recessive,severe));MYOVIIA;MYU7A;NSRD2;unconventional myosin-VIIa;USH1B.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MYO7A
Gene Fullname	myosin VIIA
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Nucleotide accession_num	NM_000260
Protein accession_num	NP_000251
Protein name	Unconventional myosin-VIIa
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Unconventional myosin-VIIa protein (838-968AA)
Formulation	50% Glycerol, 0.01M PBS, pH 7.4

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