OPHN1 Antibody

ArtNr	OACD00617
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Cell Biology Cytoskeleton Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies Immunochemistry small GTPases Rho Subfamily
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	oligophrenin-1;Opn1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	92 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	Ophn1
Gene Fullname	oligophrenin 1
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function, in hippocampal neurons. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at pre-synaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.
Nucleotide accession_num	NM_001107848
Protein accession_num	NP_001101318.1
Protein name	Oligophrenin-1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Gln634 - Ser802
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against OPHN1. It has been selected for its ability to recognize OPHN1 in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

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OACD00617-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 30.10.2025

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