ERI1 Antibody

ArtNr	OACD00695
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	3' exoribonuclease;3'-5' exonuclease ERI1;3'-5' exoribonuclease 1;3'HEXO;enhanced RNAi three prime mRNA exonuclease homolog 1;Eri-1 homolog;HEXO;histone mRNA 3' end-specific exonuclease;histone mRNA 3'-end-specific exoribonuclease;histone mRNA 3'-exonuclease 1;Protein 3'hExo;THEX1;three prime histone mRNA exonuclease 1;three prime mRNA exonuclease 1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	40 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	ERI1
Gene Fullname	exoribonuclease 1
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Nucleotide accession_num	NM_153332
Protein accession_num	NP_699163.2
Protein name	3'-5' exoribonuclease 1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Glu2 - Lys249
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against ERI1. It has been selected for its ability to recognize ERI1 in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

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Menge: 100 ul

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Lieferung vsl. bis 25.12.2025

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