GREM1 Antibody

ArtNr	OACD03987
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Myeloma Sarcoma Cell Biology Cell Culture Cytokines Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cktsf1b1;cysteine knot superfamily 1,BMP antagonist 1;down-regulated in Mos-transformed cells protein;drm;gremlin 1 homolog,cysteine knot superfamily;gremlin-1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	21 kDa
Manufacturer - Application Additional Information	WB: 0.5-2 ug/mL IHC: 5-20 ug/mL ICC: 5-20 ug/mL.
Gene symbol	Grem1
Gene Fullname	gremlin 1, DAN family BMP antagonist
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis (PubMed:15528323). Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.
Nucleotide accession_num	NM_019282
Protein accession_num	NP_062155.1
Protein name	Gremlin-1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Recombinant GREM1 (Lys25~Asp184) expressed in E.coli.
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against GREM1. It has been selected for its ability to recognize GREM1 in immunohistochemical staining and western blotting.
Concentration	0.5 mg/ml

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Menge: 100 ul

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