IL11 Antibody

ArtNr	OACD04550
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Adenocarcinoma Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies Glial Cell Markers Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IL-;IL-11;interleukin-11.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	22 kDa
Application Data	Western blotting: 0.5-2 ug/mL Immunocytochemistry in formalin fixed cells: 5-20 ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20 ug/mL Immunohistochemistry in paraffin section: 5-20 ug/mL Enzyme-linked Immunosorbent Assay: 0.05-2 ug/mL Optimal working dilutions must be determined by end user.
Gene symbol	Il11
Gene Fullname	interleukin 11
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:8913282). Also promotes the proliferation of hepatocytes in response to liver damage (PubMed:22253262). Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers (PubMed:10026196, PubMed:23948300). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3 (PubMed:23948300, PubMed:22253262).
Nucleotide accession_num	NM_008350
Protein accession_num	NP_032376.1
Protein name	Interleukin-11
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Pro25 - Leu199
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against IL11. It has been selected for its ability to recognize IL11 in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

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Menge: 100 ul

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Lieferung vsl. bis 27.11.2025

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