KREMEN1 Antibody

ArtNr	OACD05038
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Neural Mitochondrial Function Antibodies By Cell Type Carcinoma Obesity Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Lipoprotein Receptors & Associated Proteins Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	dickkopf receptor;ECTD13;KREMEN;kremen protein 1;kringle domain-containing transmembrane protein 1;kringle-coding gene marking the eye and the nose;kringle-containing protein marking the eye and the nose;KRM1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	50 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	KREMEN1
Gene Fullname	kringle containing transmembrane protein 1
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation. Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification.
Nucleotide accession_num	NM_001039570
Protein accession_num	NP_001034659.2
Protein name	Kremen protein 1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Lys157 - Gly390
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against KREMEN1. It has been selected for its ability to recognize KREMEN1 in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

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OACD05038-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 29.01.2026

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