MCAM Antibody

ArtNr	OACD05479
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies Adhesion Molecule Markers Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	1-gic;1-gicerin;AV025631;CD146;CD149;cell surface glycoprotein MUC18;gicerin;l-gicerin protein;melanoma adhesion molecule;Melanoma cell adhesion molecule;melanoma-associated antigen MUC18;Muc18;s-e;s-endo;s-gi;s-gicerin.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	67 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	Mcam
Gene Fullname	melanoma cell adhesion molecule
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration (By similarity).
Nucleotide accession_num	NM_023061
Protein accession_num	NP_075548.2
Protein name	Cell surface glycoprotein MUC18
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Tyr224 - Ile464
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against MCAM. It has been selected for its ability to recognize MCAM in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

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OACD05479-datasheet.pdf

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Menge: 100 ul

lieferbar

Lieferung vsl. bis 30.10.2025

Express-Lieferung: 1 Tage sparen

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