MMP13 Antibody

ArtNr	OACD05634
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Regulation of Appetite Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Cell Status Necrosis Mesothelioma Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Cell Stainings ECM Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Colorectal Cancer Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cl;Clg;collagenase 3;collagenase-1;interstitial collagenase;matrix metalloproteinase 13;Matrix metalloproteinase-13;Mmp;Mmp1;MMP-1;MMP-13.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	54 kDa
Species Tested	Mouse
Manufacturer - Application Additional Information	WB: 0.5-2 ug/mLICC: 5-20 ug/mLIHC: 5-20 ug/mL
Gene symbol	Mmp13
Gene Fullname	matrix metallopeptidase 13
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
Nucleotide accession_num	NM_008607
Protein accession_num	NP_032633.1
Protein name	Collagenase 3
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Recombinant MMP13 (Val66 ~ Gly238) expressed in E.coli
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against MMP13. It has been selected for its ability to recognize MMP13 in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.79 mg/ml

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Menge: 100 ul

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Lieferung vsl. bis 25.12.2025

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