Vergleich

PLA2G2A Antibody

ArtNr OACD06558
Hersteller AVIVA Systems Biology
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IP, IHC, ICC
Specific against Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias eted enzyme type IIA phospholipase A2;GIIC sPLA2;group IIA phospholipase A2;phosphatidylcholine 2-acylhydrolase 2A;phospholipase A2,group IIA (platelets,synovial fluid);phospholipase A2,membrane associated;platelet phospholipase A2;sPLA2.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
16 kDa
Application Data
Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000
Optimal working dilutions must be determined by end user.
Gene symbol
Pla2g2a
Gene Fullname
phospholipase A2 group IIA
Product format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage
2°C to 8°C|-20°C
Description of target
Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:3356705). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Acts as a ligand for integrins. Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1. Independent of its catalytic activity, activates integrins by binding to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and inducing integrin conformational changes and enhanced ligand binding to site 1. Induces cell proliferation in an integrin-dependent manner (By similarity).
Nucleotide accession_num
NM_031598
Protein accession_num
NP_113786.3
Protein name
Phospholipase A2, membrane associated
Clonality
Polyclonal
Purification
Affinity Purified; Protein A Purified
Immunogen
Range: Ser22 - Cys146
Manufacturer - Specificity
The antibody is a rabbit polyclonal antibody raised against PLA2G2A. It has been selected for its ability to recognize PLA2G2A in immunohistochemical staining and western blotting.
Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration
0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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