UBE2L3 Antibody

ArtNr	OACD08105
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Neuroscience Neuroinflammation Neural Mitochondrial Function Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Autophagy Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E2 ubiquitin-conjugating enzyme L3;E2-F1;L-UBC;UBCH7;UbcM4;ubiquitin carrier protein L3;ubiquitin conjugating enzyme E2L 3;ubiquitin-conjugating enzyme E2 L3;ubiquitin-conjugating enzyme E2-F1;ubiquitin-conjugating enzyme UBCH7;ubiquitin-protein ligase L3.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	14 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	UBE2L3
Gene Fullname	ubiquitin conjugating enzyme E2 L3
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
Nucleotide accession_num	NM_001256355
Protein accession_num	NP_001243284.1
Protein name	Ubiquitin-conjugating enzyme E2 L3
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Ser4 - Asp154
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against UBE2L3. It has been selected for its ability to recognize UBE2L3 in immunohistochemical staining and western blotting.
Formulation	PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Concentration	0.5 mg/ml

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Menge: 100 ul

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Lieferung vsl. bis 29.01.2026

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