CD130 Antibody

ArtNr	OADB00051
Hersteller	AVIVA Systems Biology
Menge	200 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Regulation of Appetite Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Flow Cytometry Primary Antibodies Glial Cell Markers
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	FC
Clon	B-K11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Citations	Chevalier, S. et al., J Biol Chem.,1996; 271(25): 14764-72. Guillet, C. et al., J Neurosci.,1999; 19(4): 1257-62. MÃ¼ller-Newen G. et al., J. Biol. Chem., 2000; 275 (7) : 4578 - 4586 Muller-Newen, G. et al., Eur J Biochem,1996; 236(3): 837-42.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD130,GP130,HIES4,CDW130,IL-6RB,sGP130
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	104 kDa
Gene symbol	CD130
Gene Fullname	interleukin 6 signal transducer
Product format	Lyophilized
Reconstitution and storage	Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Nucleotide accession_num	NM_001190981.1
Protein accession_num	NP_001177910.1
Protein name	interleukin-6 receptor subunit beta
Clonality	Monoclonal
Purification	Ion exchange chromatography
Manufacturer - Specificity	Recognises the Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein
Biological activity	Does not inhibit IL-6, IL-11, CNTF, LIF and OSM activites, Recognises the soluble antigen
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
Concentration	1 ug/uL
Storage Buffer	Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OADB00051-datasheet.pdf

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Menge: 200 ug

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Lieferung vsl. bis 27.11.2025

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