IL-13 Antibody

ArtNr	OADB00325
Hersteller	AVIVA Systems Biology
Menge	500 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Hematology Leukemia Lymphoma Cell Biology Cell Culture Cytokines Flow Cytometry Blocking Primary Antibodies Neuronal Cell Markers
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	FC, Blocking
Clon	B-B13
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	Guillot C. et al., Blood, 2003; 101 : 3325 - 3333 van der Pouw Kraan, T. C. et al., J Immunol.,1996; 156(5): 1818-23. Woerly, G. et al.,J Leukoc Biol.,2002; 72(4): 769-79.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	P600,IL-13
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Mouse IgG1
Shipping Temperature	Wet Ice
Molecular Weight	16 kDa
Gene symbol	IL-13
Gene Fullname	interleukin 13
Product format	Lyophilized
Reconstitution and storage	Store at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Nucleotide accession_num	NM_002188.2
Protein accession_num	NP_002179.2
Protein name	interleukin-13
Clonality	Monoclonal
Purification	Ion exchange chromatography
Manufacturer - Specificity	Recognises both natural and recombinant human IL-13
Biological activity	Blocks IL-13 induced proliferation on TF1 cell line
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Concentration	1 ug/uL
Storage Buffer	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

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OADB00325-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 25.12.2025

Express-Lieferung: 1 Tage sparen

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