Vergleich

IL-24 Antibody

ArtNr OADB00351
Hersteller AVIVA Systems Biology
Menge 500 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Clon B-C60
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias C49A,FISP,MDA7,MOB5,ST16,IL10B
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Category
Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype
Mouse IgG2b kappa light chain
Shipping Temperature
Wet Ice
Molecular Weight
24 kDa
Gene symbol
IL-24
Gene Fullname
interleukin 24
Product format
Liquid PBS. Carrier and preservative free.
Reconstitution and storage
Store at 2-8°C for 12 months. For longer storage, freeze aliquots.
Description of target
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Nucleotide accession_num
NM_001185156.1
Protein accession_num
NP_001172085.1
Protein name
interleukin-24
Clonality
Monoclonal
Purification
Sterile-filtered through 0.22 um.
Immunogen
Recombinant human IL-24
Manufacturer - Specificity
Recognises both natural and recombinant human IL-24 (interleukin-24) also called MDA-7 or Th2-specific cytokine FISP
Biological activity
Recognises soluble antigen
Formulation
Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
Concentration
1 ug/uL

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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