IL-6 Antibody

ArtNr	OADB00374
Hersteller	AVIVA Systems Biology
Menge	500 ug
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Blocking Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	FC, Blocking
Clon	B-E8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	Adam, N. et al., J. Virol.,2009; JVI.01601-08. Ancey, C. et al. ,Cardiovasc Res.,2003; 59(1): 78-85. Choy, E. Ann Rheum Dis.,2003; 62 Suppl 2: ii68-9. Corbellino M. et al., Blood, 2001; 98 : 3473 - 3475 Delneste Y. et al., Blood, 2003; 101 : 143 - 150 Derenne S. et al., Blood 2002; 100 : 194 - 199 Derhaschnig, U. et al.,Crit Care Med.,2004; 32(5): 1136-40. Dore, P. et al.,Clin Exp Immunol.,1997; 107(1): 182-8. Foussat, A. et al.,Eur Cytokine Netw.,1999; 10(4): 501-8. Garban, F. et al., Blood,2006; 107(9): 3474-80. Gu, Z. J. et al., Leukemia,2000; 14(1): 188-97. Haddad E. et al., Blood, 2001; 97 : 1590 - 1597 Jego G. et al., Blood, 2001; 97(6) : 1817 - 1822 Jourdan, M. et al.,Br J Haematol.,1998; 100(4): 637-46. Kalai, M. et al.,Blood,1997; 89(4): 1319-33. Kricka, L. J., Clin Chem.,1999; 45(7): 942-56. Kube, D. et al., Blood,2001; 98(3): 762-70. Leblond, V. et al., J Clin Oncol.,2001; 19(3): 772-8. Lelievre, E. et al.,Cytokine,1998; 10(11): 831-40. Lu, Z. Y. et al., Blood,1995; 86(8): 3123-31. Lu, Z. Y. et al., Blood,1995; 85(9): 2521-7. Mahtouk K. et al., Blood, 2004; 103(5): 1829 Marfaing-Koka, A. et al., J Acquir Immune Defic. Syndr. Hum. Retrovirol.,1996; 11(1): 59-68. Menetrier-Caux, C. et al., Cancer Res.,2001; 61(7): 3096-104. Moreau P. et al., Blood, 2006; 107 (1) :397-403 Moreaux J. et al., Blood, 2004; 103(8) : 3148 - 3157 Park, C. S. et al.,Am J Respir Crit Care Med., 2000; 162(3 Pt 1): 1162-8. Pieraut, S. et al., J. Neurosci.,2011;31:13516 -13526 Smith, M. D. et al., Ann Rheum Dis.,2003; 62(4): 303-7. Song, X. Y. et al.,Mol Interv.,2002; 2(1): 36-46 Sprynski, A. C. et al., Blood,2009; blood-2008-07-170464. Srivani, R. et al.,Current Science,2003;84(3): 434-438 Stenger, S. et al.,J Immunol.,1998; 161(7): 3582-8
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CDF,HGF,HSF,BSF2,IL-6,BSF-2,IFNB2,IFN-beta-2
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Mouse IgG1
Shipping Temperature	Wet Ice
Molecular Weight	24 kDa
Gene symbol	IL-6
Gene Fullname	interleukin 6
Product format	Lyophilized
Reconstitution and storage	Store at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
Nucleotide accession_num	NM_000600.4
Protein accession_num	NP_000591.1
Protein name	interleukin-6
Clonality	Monoclonal
Purification	Ion exchange chromatography
Manufacturer - Specificity	Recognises both natural and recombinant human IL-6
Biological activity	Blocks IL-6 induced proliferation on B9 cells Inhibits IL-6 binding to its receptor
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Concentration	1 ug/uL
Storage Buffer	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

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OADB00374-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 25.12.2025

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