TNFRSF12A Antibody

ArtNr	OAEE00170
Hersteller	AVIVA Systems Biology
Menge	0.1 mg (C100)
Kategorie	Oncology Antibodies By Cell Type Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies Functional Assays
Typ	Antibody Monoclonal
Applikationen	WB, FC, IHC, FA
Clon	ITEM-4
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2b
Purity	> 95% (by SDS-PAGE)
Citations	Roos C, Wicovsky A, MÃ¼ller N, Salzmann S, Rosenthal T, Kalthoff H, Trauzold A, Seher A, Henkler F, Kneitz C, Wajant H: Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway. J Immunol. 2010 Aug 1;185(3):1593-605. Nakayama M, Ishidoh K, Kojima Y, Harada N, Kominami E, Okumura K, Yagita H: Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. J Immunol. 2003 Jan 1;170(1):341-8. Sanz AB, Sanchez-Niño MD, Carrasco S, Manzarbeitia F, Ruiz-Andres O, Selgas R, Ruiz-Ortega M, Gonzalez-Enguita C, Egido J, Ortiz A: Inflammatory cytokines and survival factors from serum modulate tweak-induced apoptosis in PC-3 prostate cancer cells. PLoS One. 2012;7(10):e47440. Yoriki R, Akashi S, Sho M, Nomi T, Yamato I, Hotta K, Takayama T, Matsumoto S, Wakatsuki K, Migita K, Yagita H, Nakajima Y: Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer. Exp Ther Med. 2011 Jan;2(1):103-108
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD266;FGF-inducible 14;fibroblast growth factor-inducible immediate-early response protein 14;FN14;tumor necrosis factor receptor superfamily member 12A;TWEAKR;tweak-receptor;type I transmembrane protein Fn14.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	Flow cytometry\|Functional assay\|Immunohistochemistry-Frozen\|Western blot
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	TNFRSF12A
Gene Fullname	TNF receptor superfamily member 12A
Product format	Phosphate buffered saline (PBS), pH 7.4
Reconstitution and storage	2°C to 8°C
Description of target	Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Nucleotide accession_num	NM_016639.2
Protein accession_num	NP_057723.1
Protein name	Tumor necrosis factor receptor superfamily member 12A
Clonality	Monoclonal
Purification	Purified
Immunogen	human CD266-transfected P815 cells
Manufacturer - Specificity	The mouse monoclonal antibody ITEM-4 recognizes CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis.
Formulation	Low endotoxin
Concentration	1 mg/ml
Storage Buffer	Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.

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Menge: 0.1 mg (C100)

lieferbar

Lieferung vsl. bis 08.01.2026

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