LAMP1 Antibody

ArtNr	OAEE00598
Hersteller	AVIVA Systems Biology
Menge	100 tests (T100)
Kategorie	Neuroscience Molecular Targets for Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Flow Cytometry Immunohistochemistry Western Blot Immunocytochemistry Autophagy Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC
Clon	H4A3
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Primate
Host	Mouse
Isotype	IgG1
Konjugat/Tag	APC
Citations	Mao H, Tu W, Liu Y, Qin G, Zheng J, Chan PL, Lam KT, Peiris JS, Lau YL: Inhibition of human natural killer cell activity by influenza virions and hemagglutinin. J Virol. 2010 May;84(9):4148-57. Yu CI, Gallegos M, Marches F, Zurawski G, Ramilo O, GarcÃa-Sastre A, Banchereau J, Palucka AK: Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines. Blood. 2008 Nov 1;112(9):3671-8. Tomescu C, Chehimi J, Maino VC, Montaner LJ: NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement forIFN-mediated NK activation by plasmacytoid dendritic cells. J Immunol. 2007 Aug 15;179(4):2097-104. Carlsten M, BjÃ¶rkstrÃ¶m NK, Norell H, Bryceson Y, van Hall T, Baumann BC, Hanson M, Schedvins K, Kiessling R, Ljunggren HG, Malmberg KJ: DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells. Cancer Res. 2007 Feb 1;67(3):1317-25. Marcenaro S, Gallo F, Martini S, Santoro A, Griffiths GM, AricÃ³ M, Moretta L, Pende D: Analysis of natural killer-cell function in familial hemophagocyticlymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4defect and discriminates between genetic subtypes of the disease. Blood. 2006 Oct 1;108(7):2316-23., Furuta K, Ikeda M, Nakayama Y, Nakamura K, Tanaka M, Hamasaki N, Himeno M, Hamilton SR, August JT: Expression of lysosome-associated membrane proteins in human colorectal neoplasms and inflammatory diseases. Am J Pathol. 2001 Aug;159(2):449-55. And many other. Mane SM, Marzella L, Bainton DF, Holt VK, Cha Y, Hildreth JE, August JT: Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 1989 Jan;268(1):360-78. Deetz CO, Hebbeler AM, Propp NA, Cairo C, Tikhonov I, Pauza CD: Gamma interferon secretion by human Vgamma2Vdelta2 T cells after stimulation with antibody against the T-cell receptor plus the Toll-Like receptor 2 agonistPam3Cys. Infect Immun. 2006 Aug;74(8):4505-11.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD107 antigen-like family member A;CD107a;LAMP-1;LAMPA;LGP120;lysosome-associated membrane glycoprotein 1;lysosome-associated membrane protein 1.
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human, Mouse, Non-human Primate
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	LAMP1
Gene Fullname	lysosomal associated membrane protein 1
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Nucleotide accession_num	NM_005561.3
Protein accession_num	NP_005552.3
Protein name	Lysosome-associated membrane glycoprotein 1
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	Human PBMC
Manufacturer - Specificity	The mouse monoclonal antibody H4A3 recognizes CD107a, an approximately 100-120 kDa glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.
Formulation	APC
Concentration	10 ul / test
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

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Menge: 100 tests (T100)

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