CD180 Antibody

ArtNr	OAEE00688
Hersteller	AVIVA Systems Biology
Menge	100 tests (T100)
Kategorie	Neuroscience Neural Lineage Markers Antibodies Flow Cytometry Immunoprecipitation Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC
Clon	G28-8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	APC
Citations	Olson NE, Graves JD, Shu GL, Ryan EJ, Clark EA: Caspase activity is required for stimulated B lymphocytes to enter the cell cycle. J Immunol. 2003 Jun 15;170(12):6065-72. Clark EA, Shu GL, LÃ¼scher B, Draves KE, Banchereau J, Ledbetter JA, Valentine MA: Activation of human B cells. Comparison of the signal transduced by IL-4 to four different competence signals. J Immunol. 1989 Dec 15;143(12):3873-80. Valentine MA, Clark EA, Shu GL, Norris NA, Ledbetter JA: Antibody to a novel 95-kDa surface glycoprotein on human B cells induces calcium mobilization and B cell activation. J Immunol. 1988 Jun 15;140(12):4071-8. Kikuchi Y, Koarada S, Tada Y, Ushiyama O, Morito F, Suzuki N, Ohta A, Horiuchi T, Miyake K, Nagasawa K: Difference in B cell activation between dermatomyositis and polymyositis:analysis of the expression of RP105 on peripheral blood B cells. Ann Rheum Dis. 2001 Dec;60(12):1137-40. Divanovic S, Trompette A, Petiniot LK, Allen JL, Flick LM, Belkaid Y, Madan R, Haky JJ, Karp CL: Regulation of TLR4 signaling and the host interface with pathogens and danger:the role of RP105. J Leukoc Biol. 2007 Aug;82(2):265-71. Yazawa N, Fujimoto M, Sato S, Miyake K, Asano N, Nagai Y, Takeuchi O, Takeda K, Okochi H, Akira S, Tedder TF, Tamaki K: CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes. Blood. 2003 Aug 15;102(4):1374-80. Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, Finberg RW, Tarakhovsky A, Vogel SN, Belkaid Y, Kurt-Jones EA, Karp CL: Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol. 2005 Jun;6(6):571-8.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD180 antigen;LY64;Ly78;lymphocyte antigen 64;lymphocyte antigen-64,radioprotective,105kDa;radioprotective 105 kDa protein;RP105.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CD180
Gene Fullname	CD180 molecule
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
Nucleotide accession_num	NM_005582.2
Protein accession_num	NP_005573.2
Protein name	CD180 antigen
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	Human tonsillar B cells
Manufacturer - Specificity	The mouse monoclonal antibody G28-8 recognizes CD180, a 95-105 kDa TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells.
Formulation	APC
Concentration	10 ul / test
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

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Menge: 100 tests (T100)

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