TNFSF10 Antibody

ArtNr	OAEE00751
Hersteller	AVIVA Systems Biology
Menge	0.1 mg (C100)
Kategorie	Metabolism Glucose Homeostasis Antibodies Flow Cytometry Primary Antibodies Functional Assays
Typ	Antibody Monoclonal
Applikationen	FC
Clon	200000
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	PE
Citations	Plasilova M, Zivny J, Jelinek J, Neuwirtova R, Cermak J, Necas E, Andera L, Stopka T: TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasiaprogenitors. Leukemia. 2002 Jan;16(1):67-73. Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC: Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells. Cancer Res. 2005 Jun 1;65(11):4799-808.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Apo-2 ligand;Apo-2L;APO2L;CD253;chemokine tumor necrosis factor ligand superfamily member 10;TL2;TNF-related apoptosis inducing ligand TRAIL;TNF-related apoptosis-inducing ligand;TNLG6A;TRAIL;tumor necrosis factor (ligand) family,member 10;tumor necrosis factor (ligand) superfamily,member 10;tumor necrosis factor apoptosis-inducing ligand splice variant delta;tumor necrosis factor ligand 6A;tumor necrosis factor ligand superfamily member 10;tumor necrosis factor superfamily member 10.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Conjugate / Tag	R-PE
Shipping Temperature	Wet Ice
Gene symbol	TNFSF10
Gene Fullname	TNF superfamily member 10
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:26457518, PubMed:10549288). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Nucleotide accession_num	NM_001190942.1; NM_003810.3
Protein accession_num	NP_001177871.1; NP_003801.1
Protein name	Tumor necrosis factor ligand superfamily member 10
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	Recombinant soluble fragment (aa 95-281) of human TRAIL.
Manufacturer - Specificity	The antibody 2E5 reacts with TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
Formulation	PE
Concentration	0.1 mg/ml
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

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Menge: 0.1 mg (C100)

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