GP9 Antibody

ArtNr	OAEE00861
Hersteller	AVIVA Systems Biology
Menge	100 tests (T100)
Kategorie	Neuroscience Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC
Clon	GR-P
Specific against	Human (Homo sapiens), Dog (Canine, Canis lupus familiaris)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	FITC
Citations	Din JN, Aftab SM, Jubb AW, Carnegy FH, Lyall K, Sarma J, Newby DE, Flapan AD: Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans. Eur J Clin Nutr. 2011 Feb;65(2):234-9. Vettore S, Scandellari R, Moro S, Lombardi AM, Scapin M, Randi ML, Fabris F: Novel point mutation in a leucine-rich repeat of the GPIbalpha chain of the platelet von Willebrand factor receptor, GPIb/IX/V, resulting in an inherited dominant form of Bernard-Soulier syndrome affecting two unrelated families: the N41H variant. Haematologica. 2008 Nov;93(11):1743-7. Brown SB, Clarke MC, Magowan L, Sanderson H, Savill J: Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program. J Biol Chem. 2000 Feb 25;275(8):5987-96. Harding SA, Din JN, Sarma J, Josephs DH, Fox KA, Newby DE: Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin. Heart. 2006 Nov;92(11):1635-8. Leukocyte Typing IV., Knapp W. et al. (Eds.), Oxford University Press (1989)
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD42a;glycoprotein 9;GPIX;platelet glycoprotein IX.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GP9
Gene Fullname	glycoprotein IX platelet
Product format	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
Nucleotide accession_num	NM_000174.4; XM_005247374.3
Protein accession_num	NP_000165.1; XP_005247431.1
Protein name	Platelet glycoprotein IX
Clonality	Monoclonal
Purification	Purified by size-exclusion chromatography
Immunogen	Human acute lymphoblastic leukemia cells
Manufacturer - Specificity	The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets. HLDA IV.; WS Code P 35
Formulation	FITC
Concentration	4 ul / test
Storage Buffer	The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

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Menge: 100 tests (T100)

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