LMNA Antibody

ArtNr	OAGA01481
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FPL,IDC,LFP,CDDC,EMD2,FPLD,HGPS,LDP1,LMN1,LMNC,MADA,PRO1,CDCD1,CMD1A,FPLD2,LMNL1,CMT2B1,LGMD1B
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene symbol	LMNA
Gene Fullname	lamin A/C
Product format	Liquid. 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Clonality	Polyclonal
Purification	Purified by antigen-affinity chromatography.
Immunogen	Recombinant protein encompassing a sequence within the center region of human Lamin A/C. The exact sequence is proprietary.
Concentration	0.27mg/ml

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OAGA01481-datasheet.pdf

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Menge: 100 ul

lieferbar

Lieferung vsl. bis 08.01.2026