DMPK Antibody

ArtNr	OAGA01529
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies By Organ Skin Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DM,DM1,DMK,MDPK,DM1PK,MT-PK
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene symbol	DMPK
Gene Fullname	dystrophia myotonica-protein kinase
Product format	Liquid. 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5, 000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Clonality	Polyclonal
Purification	Purified by antigen-affinity chromatography.
Immunogen	Recombinant protein encompassing a sequence within the center region of human DMPK. The exact sequence is proprietary.
Concentration	1mg/ml

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OAGA01529-datasheet.pdf

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Menge: 100 ul

lieferbar

Lieferung vsl. bis 08.01.2026