APEX1 Antibody

ArtNr	OAGA03611
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies CHiP Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IP, ICC, IHC-P, CHIP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	APE,APX,APE1,APEN,APEX,HAP1,REF1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, IP: 1:100-1:500, WB: 1:500-1:20000, ChIP assay. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene symbol	APEX1
Gene Fullname	apurinic/apyrimidinic endodeoxyribonuclease 1
Product format	Liquid
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Nucleotide accession_num	NM_001244249.1
Protein accession_num	NP_001231178.1
Protein name	DNA-(apurinic or apyrimidinic site) lyase
Clonality	Polyclonal
Purification	Purified by antigen-affinity chromatography.
Immunogen	Recombinant protein encompassing a sequence within the center region of human APE1. The exact sequence is proprietary.
Concentration	1 mg/ml
Storage Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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OAGA03611-datasheet.pdf

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Menge: 100 ul

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