RBBP4 Antibody

ArtNr	OAGA05090
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies CHiP Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, ICC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NURF55,RBAP48,lin-53
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene symbol	RBBP4
Gene Fullname	RB binding protein 4, chromatin remodeling factor
Product format	Liquid
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
Nucleotide accession_num	NM_001135255.1
Protein accession_num	NP_001128727.1
Protein name	histone-binding protein RBBP4
Clonality	Polyclonal
Purification	Purified by antigen-affinity chromatography.
Immunogen	Recombinant protein encompassing a sequence within the center region of human RbAp48. The exact sequence is proprietary.
Concentration	0.65 mg/ml
Storage Buffer	0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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