RSPO1 Antibody

Polyclonal Antibody

Wet Ice

RSPO1

Liquid

This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

NP_001033722.1

Polyclonal

Recombinant protein encompassing a sequence within the center region of human RSPO1. The exact sequence is proprietary.

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.