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CARMA2 Antibody - C-terminal

ArtNr OAPB01414
Hersteller AVIVA Systems Biology
Menge 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias bcl10-interacting maguk protein 2;BIMP2;CARD-containing MAGUK protein 2;CARMA2;caspase recruitment domain-containing protein 14;PRP;PSORS2;PSS1.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Gene symbol
CARD14
Gene Fullname
caspase recruitment domain family member 14
Product format
Liquid. CARMA2 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases (PubMed:11278692, PubMed:21302310, PubMed:27113748, PubMed:27071417). May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis.
Nucleotide accession_num
NM_001257970.1
Protein accession_num
https://www.ncbi.nlm.nih.gov/protein/NP_077015
Protein name
Caspase recruitment domain-containing protein 14|caspase recruitment domain-containing protein 14 isoform 1 [Homo sapiens]
Clonality
Polyclonal
Purification
Affinity Purified
Immunogen
CARMA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human CARMA2. The immunogen is located within the last 50 amino acids of CARMA2.
Concentration
1 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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