Human TLR6 Antibody

ArtNr	OASB01315
Hersteller	AVIVA Systems Biology
Menge	0.1 mg
Kategorie	Neuroscience Neural Lineage Markers Antibodies Primary Antibodies Neurodegeneration Markers
Typ	Antibody Monoclonal
Clon	3B6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	Unconjugated
Citations	1. Hajjar, A.M., D.S. O'Mahony, A. Ozinsky, D.M. Underhill, A. Aderem, S.J. Klebanoff, and C.B. Wilson. 2001. J. Immunol. 166:15 2. Takeuchi, O., T. Kawai, P.F. Muhlradt, M. Morr, J.D. Radolf, A. Zychlinsky, K. Takeda, and S. Akira. 2001. Int. Immunol. 13:933 3. Bulut, Y., E. Faure, L. Thomas, O. Equils, and M. Arditi. 2001. J. Immunol. 167:987 4. Akira, S., and K. Takeda. 2004. Nat. Rev. Immunol. 4:499 5. Takeuchi, O. T. Kawai, H. Sanjo, N.G. Copeland, D.J. Gilbert, N.A. Jenkins, K. Takeda, and S. Akira. 1999. Gene 231:59 6. Muzio, M., G. Gioacchino, S. Saccani, M. Lavrero, and A. Mantovani. 1998. J. Exp. Med. 187:2097.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD286
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Species Tested	Human
Manufacturer - Application Additional Information	Flow cytometry, Enzyme-Linked-Immunosorbent-Assay (ELISA)
Gene symbol	TLR6
Gene Fullname	Toll-like receptor 6
Reconstitution and storage	Store at 2-8C
Description of target	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.
Nucleotide accession_num	NM_006068.4
Protein accession_num	NP_006059.2ï»¿
Protein name	toll-like receptor 6
Clonality	Monoclonal
Dilution	Flow Cytometry: Purified antibody 1ug/106 ELISA: Purified antibody 1:3, 000-1:5, 000
Manufacturer - Specificity	TLR6
Concentration	0.5 mg/mL

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