Human MMP-3 Antibody : HRP

Monoclonal Antibody

Wet Ice

Enzyme-Linked-Immunosorbent-Assay (ELISA), Immunohistochemistry (frozen and paraffin embedded sections)

Stromelysin-1

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP' s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

NP_002413.1

Monoclonal

ELISA: Purified antibody
HRP conjugate
1:3, 000-1:8, 000
1:1, 000-1:4, 000
Immunohistochemistry: Purified antibody
HRP conjugate
£ 2 mg/mL
1:1, 000-1:2, 000

Lot specific